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Latest Surrogacy News
No danger to pregnancy through single embryo
transfers
India
Times
July 1, 2003
LONDON: In a
first study, doctors in Australia have found that
transferring one embryo instead of two during an IVF cycle
does not reduce the chances of a woman having a baby, when
frozen as well as fresh embryos are taken into account.
Dr Jim Catt, Embryology director of
Sydney IVF, Australia, and his colleagues have conducted the
study looking at cumulative pregnancy and live birth rates
that took into account the transfer of previously frozen as
well as fresh embryos.
In 382 IVF patients aged under 38, who
had at least two five-day-old embryos that were suitable for
transfer or freezing, the cumulative live birth rate was
exactly the same whether one or two embryos had been
transferred in the first cycle.
Women who chose to have two embryos
transferred in one cycle had a higher chance of success
first time round - their live birth rate was 50 percent s
opposed to 36 percent among the women who chose to have a
single embryo transferred.
But when the previously frozen embryos
were subsequently transferred to the women who had failed to
become pregnant in the first cycle, the cumulative live
birth rates for both groups of women was 60 percent.
In addition, single embryo transfer
(SET) carried fewer risks to mothers and foetuses. Among the
107 women out of 382 who chose to have SET, only three sets
of twins from the subsequent frozen embryo transfers were
delivered, while amongst the 275 women who chose to have two
embryos transferred there were 90 twin pregnancies, four of
which resulted in miscarriages with the loss of both twins
and 18 of which resulted in the loss of one twin.
The live birth rate per embryo transfer
amongst the SET group was 36 percent and 35 percent in the
group choosing to have dual embryo transfer.
"This is the first time that a study of
cumulative pregnancy and live birth rates with five-day-old
SET embryos has been conducted. Under the conditions of this
study, twin pregnancies can be reduced drastically without
compromising a patient's chance of a successful pregnancy.
All patients younger than 38 are now offered SET and
approximately 70 percent of them accept, with an acceptable
ongoing pregnancy rate of 40 percent", said Dr Catt.
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